By Paul F. Torrence
Antiviral Drug Discovery provides readers a state-of-the-art view of ways chemical innovations are being mobilized to improve novel techniques that might successfully confront rising illnesses and biowarfare. one of many subject matters mentioned are smallpox, the Ebola virus, influenza, SARS, arenaviruses and flaviviruses. every one bankruptcy discusses hypothetical techniques for the invention of suitable antiviral brokers, contemporary findings on the topic of biochemistry or drug discovery, and advances within the additional improvement of verified leads within the quarter. well timed and informative, this booklet essentially delineates the efforts being made to advance new and potent broad-spectrum antiviral brokers.
Read or Download Antiviral Drug Discovery for Emerging Diseases and Bioterrorism Threats PDF
Similar viral books
The 2009 global Malaria file summarizes info bought from 108 malaria endemic international locations and different assets and updates the research awarded within the 2008 document. It highlights development made in assembly the area overall healthiness meeting pursuits for malaria to be accomplished through 2010 and 2015, and new ambitions on malaria removal inside the worldwide Malaria motion Plan.
An Atlas of the scientific Microbiology of Infectious ailments, quantity : Viral, Fungal, and Parasitic brokers is the second one of a chain and companion to quantity One, which offers with Microbiological and scientific Attributes. choked with hugely educational visible pictures, this atlas covers ordinary and bizarre shows of viral, fungal and parasitic brokers and gives insightful reviews supporting their identity and scientific importance.
- Parasites, Pathogens, and Progress: Diseases and Economic Development
- Smallpox: The Fight to Eradicate a Global Scourge
- Zika in Focus: Postnatal Clinical, Laboratorial and Radiological Aspects
- MRSA (Methicillin-Resistant Staphylococcus aureus)
Additional resources for Antiviral Drug Discovery for Emerging Diseases and Bioterrorism Threats
Davis, K. Viral encephalitides. In Textbook of Military Medicine, Office of the Surgeon General, Department of the Army, Washington, DC, 1997, pp. 561–589. 13. ; Handelman, S. Biohazard. Random House, New York, 1999. 14. ; Buller, R. M. L. Looking back at smallpox. Clin. Infect. Dis. 2004, 38, 882–890. 15. Basler, C. ; Klenk, H. ; Palese, P. The Ebola virus VP35 protein functions as a type I IFN antagonist. Proc. Natl. Acad. Sci. USA 2000, 97, 12289–12294. 16. Basler, C. ; Klenk, H. ; Garcia-Sastre, A.
The only viruses in this category are a number of positive-sense RNA viruses known as encephalitis agents, since they cause febrile illness accompanied in a variable percentage of cases by infection of the central nervous system. 11,12 Their introduction by the respiratory route is expected to cause incapacitating, but generally nonfatal, illness in a high percentage of those exposed. However, aerosol transmission may also result in an increased incidence of neurological complications, since viral infection of the nasal epithelium and olfactory nerve offers a passageway into the central nervous system.
Dis. 2002, 8, 225–229. 8. ; Bartlett, J. ; Ascher, M. ; Jahrling, P. ; Osterholm, M. ; Russell, P. ; Tonat, K. Smallpox as a biological weapon: medical and public health management. JAMA 1999, 281, 2127–2137. 9. Jahrling, P. B. Viral hemorrhagic fevers. In Textbook of Military Medicine, Office of the Surgeon General, Department of the Army, Washington, DC, 1997, pp. 591–602. 10. ; Peters, C. ; Schmaljohn, A. ; Hughes, J. ; Jahrling, P. ; Johnson, K. ; Ascher, M. ; Breman, J. ; Eitzen, E. M. ; Henderson, D.